5-Pyrimidinecarbonyl chloride (7CI,9CI)

5-Pyrimidinecarbonyl chloride (7CI,9CI) - Names and Identifiers

Name	pyrimidine-5-carbonyl chloride
Synonyms	40929-48-4 5-Pyrimidinecarbonyl chloride pyrimidine-5-carbonyl chloride 5-Pyrimidinecarbonyl chloride (7CI,9CI)
CAS	40929-48-4
InChI	InChI=1/C5H3ClN2O/c6-5(9)4-1-7-3-8-2-4/h1-3H

5-Pyrimidinecarbonyl chloride (7CI,9CI) - Physico-chemical Properties

Molecular Formula	C5H3ClN2O
Molar Mass	142.54
Density	1.393g/cm³
Boling Point	230.8°C at 760 mmHg
Flash Point	93.4°C
Vapor Presure	0.0646mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.551

5-Pyrimidinecarbonyl chloride (7CI,9CI) - Introduction

pyrimidine-5-carbonyl chloride is an organic compound whose chemical formula is C5H2ClNO. The following is a description of the nature, use, preparation and safety information of pyrimidine-5-carbonyl chloride:

Nature:
-Appearance: The pyrimidine-5-carbonyl chloride is a colorless to slightly yellow solid.
-Solubility: It can be dissolved in many organic solvents, such as ethanol, ether and dimethylformamide.
-Stability: It is relatively stable at room temperature, but sensitive to moisture and high temperature.

Use:
-Chemical synthesis: pyrimidine-5-carbonyl chloride are commonly used in organic synthesis, can be used as reactants or reagents, to participate in alkylation, dehydration or acylation reactions.
-Pharmaceutical industry: It has a wide range of applications in drug synthesis, and is often used as an intermediate for the synthesis of pyrimidine anticancer drugs and antiviral drugs.
-Pesticide industry: pyrimidine-5-carbonyl chloride can also be used as intermediates for pesticides and insecticides.

Preparation Method:
pyrimidine-5-carbonyl chloride can generally be obtained by reacting pyrimidine with a chlorinated acid (such as thionyl chloride, phosphorus chloride). The specific preparation method may be appropriately adjusted and optimized as required.

Safety Information:
- pyrimidine-5-carbonyl chloride are irritating to the skin, eyes and respiratory tract and are potentially harmful to health.
-Wear appropriate protective gloves, glasses and a protective mask to prevent contact during operation.
-Operate in a well-ventilated place to avoid inhaling its vapors.
-Keep sealed when stored, away from fire and high temperature environment.
-During use and handling, please follow the corresponding safety operation procedures and protective measures.

Last Update：2024-04-09 02:00:45